The District Municipality of Muskoka, more generally referred to as the District of Muskoka or Muskoka, is a regional municipality in Central Ontario, Canada. Muskoka extends from Georgian Bay in the west, to the northern tip of Lake Couchiching in the south, to the western border of Algonquin Provincial Park in the east. A two-hour drive north of Toronto, Muskoka spans 6,475 km2 (2,500 sq mi). Muskoka has some 1,600 lakes, making it a popular cottaging destination.

Muskoka is an area populated with several villages and towns, farming communities, and lakeside vacation hotels and resorts near to golf courses, country clubs, and marinas. The regional government seat is Bracebridge and the largest population centre is Huntsville.

Muskoka is geographically located within the Central Ontario region of the province, although it is treated as part of Northern Ontario by some government programs.

Muskoka is a summer destination for Toronto residents and was the #1 most searched Canadian destination for vacation rentals in 2017.[3] The Muskoka region was also ranked #1 for best trips of 2011 by National Geographic, and was a finalist for the same distinction in 2012.